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CC2652R: What is the best practice for MCU Serialization in product line?

Part Number: CC2652R
  1. MAC address is a kind of unique ID, but for some reason it's not enough for our purpose 
  2. Found that MSP Gang can do serialization for MSP430 chip, but not for SimpleLink MCUs. 
  3. in TI files, it is said there is Device identity: Unique and immutable die ID and Bluetooth address. Is there any API to read this "die ID"?  http://www.ti.com/lit/ml/swpb016a/swpb016a.pdf
  4. The only idea left is: modifying hex file before flashing. Is there something like "best practice" on this?
    1. e.g. which page to choose?
    2. how to prevent these fields been modified after production?
    3. will there be potential impact on OAD image checksum calculation?