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Interface CC3200 with CC2538 for Implementing Zigbee-Wi-Fi GW

Other Parts Discussed in Thread: CC2538, CC2650, CC3200

Hi, 

I want to replace CC2650 in the following Reference Design by CC2538 
In order to do my own Zigbee - Wi-Fi gateway 

www.ti.com/.../tidc-ble-to-wifi-iot-gateway

Can I use CC2538 Instead of CC2650 in order to act as ZNP (ZigBee Network Processor) 
and keep the CC3200 for Wi-Fi side ?

is there any guide me for interfacing CC2538 with host controller through UART or SPI ?

Thanks In Advance