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RTOS/CC2538EMK: ZigBee end device can we control by coordinator

Part Number: CC2538EMK
Other Parts Discussed in Thread: Z-STACK

Tool/software: TI-RTOS

We have one ZigBee mesh topology doubt

 if end device(e1) connected to the router(r1).  And the end device(e1) within the range of coordinator(c1) and some other router(r2,r3).

if coordinator(c1) to router(r1) communication broken then coordinator can directly send the command to end device or not?

In below diagram, have explained my scenario. Can anyone clear this doubt?