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Will PCB layout impact the SNR and THD for TPA3110D2?

Other Parts Discussed in Thread: TPA3110D2

Dear Sir,

  We've met a strange problem recently. We using 2 pieces of TPA3110D2 for a 4X4 OHM speaker, and one pieces of TPA3110D2  SNR is 50dB, the other is 30dB. The two pieces of TPA3110D2 circuit are the same, the only diference is Layout.  Will Layout impact so much?

 4645.TPA3110D2-AMP.pdf