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PCA9539: PCA9539

Part Number: PCA9539

Hi, 

What is the status of the I2C pins of PCA9539 when PCA9539 is not powered? ( the I2C bus is pull-up to another power rail)

We have lots of I2C devices on the board. We need to use one I2C bus to connect with all these I2C devices and PCA9539. Those devices are not in the same power rail as PCA9539.

My concern is if  PCA9539 is not powered, will it impact the I2C reading&writing of other devices which is powered normally?  If the I2C pin does not acts as High-Z when PCA9539 is not powered, it will impact the behavior of the whole I2C bus, right?