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DS90UB954-Q1: USB2ANY makes all I2C communications fail

Part Number: DS90UB954-Q1
Other Parts Discussed in Thread: USB2ANY, ALP

I have run the MAP tool successfully on another platform now I am trying it on a new platform, I have the USB2ANY board plugged in (only SCL and SDA) and can see the I2C communications are fine but as soon as I open up the Analog Launchpad program all I2C communications fails and when I look at the oscilloscope the SDA line is pulled HIGH and SCL pulled LOW. Do you have any idea what the issue here could be?

Cheers,

Mathieu