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XIO2001: M66EN and PCIR connections

Part Number: XIO2001

hi,

I am using XIO2001 to interface with mil1553 devices.These devices are 3.3V tolerant and support only upto 33MHz.. To connect to these devices what are the connections on M66EN and PCIR pins of  XIO2001.

Since i found from datasheet that to use 33MHz, PCIR must be connected to 5V(secondary bus voltage),but here the devices are 3.3V tolerant.

Thanks.