When we cycle power the PWDN_N pin (pin 44) is pulled low (0V). If we manually reset the device via RESET_N (pin 43), for the duration of the reset the PWDN_N pin is released and pulls up to 3.3V via the pull resistor and then when the reset is deasserted the PWDN_N pin is then asserted low again, which goes against the datasheet that says this pin is by default an input.
This behaviour does not make sense as the device is supposed to have PWDN_N (pin 44) configured as an input by default to allow for external control of power-down mode. We have a resistor-cap filter on the RESET_N pin with a duration greater than 200ms before the voltage on this pin is greater than 2V (the Vih minimum limit) so the device should be powering up sufficiently.
We are also operating with 2 voltage supply rails (so have thus left the 1P8 pins floating as the datasheet requires).