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TCAN1043-Q1: VIO supply vs MCU supply

Part Number: TCAN1043-Q1
Other Parts Discussed in Thread: TCAN1043

Hello 

can I use 2 independent 5V supplies (with same GND) for VIO and the supply of the MCU connected with TCAN1043(A)-Q1.

VIO is the pull up of TXD and RXD for my understanding. Is this ok?

Thx 

Martin