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TCA9517A: Can VCCA higher than VCCB

Part Number: TCA9517A
Other Parts Discussed in Thread: TCA9517-Q1

Hi Team

Could you help advice can I use TCA9517A with VCCA=5V and VCCB =3.3V? because sideB VOL is higher than isolator VIL, so I have to connect TCA9517A side A to isolator.

And can Enable pin connect to 3.3V directly?

Thanks for support!