When bringing up the PCB that has 3 PCA9535's populated to appx 60C, I am noticing that the I2C line is being driven low before my MCU (master) attempts to communicate with the device.

The MCU is located outside the temperature chamber, so I know it is isolated to the ICs on the board. I have powered off the other ICs that share the line and still seeing this behavior. Once I bring the temperature back down to appx 25C, I no longer see this problem. This is also not an issue at -40C. It looks like the PCA9535 are still operating, as the GPOs are configured before the temperature cycling and they are still outputting 5V.

Not sure if this is a known problem or why there is a temperature dependency here.