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DS90UB928Q-Q1: DS90UB928Q-Q1: Register Configuration for GPIO Function

Part Number: DS90UB928Q-Q1

Tool/software:

Hello, I am using the 928 deserializer and the local GPIO_REG5 pin for GPIO control. The corresponding registers are shown below.

According to the manual, the default register value is 0x00, then the default is to output low level, and my requirement is also to output low, do I still need to configure bit0=1 specially?
I have this question because bit0 corresponds to these two values Enable normal operation and Enable GPIO operation, I don't understand them very well, what is the difference between the default normal operation and GPIO operation?