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THVD1454: Termination resistor ON or OFF

Part Number: THVD1454

Hi team,

Regarding the criteria for switching a termination resistor ON or OFF, is it correct to understand that it depends on the position of the device on the communication line?
Specifically, is it correct to design the system so that the termination resistor is ON for end nodes and OFF for middle nodes?

Best Regards,

Shota