TUSB7340: USB port to work and have data flow at the same timing

Hi Team,

As the title, I have customer that might need to expand the SOC/PCIE to 4 USB ports.

But could TUSB7340 four downstream USB ports work at the same time ? With different data flow and direction ?

Or must it work one by one, that's to disable the other 3 while one USB is working ?

Thanks for your help.