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TLK1221: serdes signal failures

Part Number: TLK1221

TLK1221 works find in loopback mode: input TD0~TD9 will pass to RD0~RD9 as it designed to. however, it two chips linked together, RD0~RD9 in receving chip will show different signal from TD0~TD9 in transimitter side. what could be the reason for that?