Hello na na,
The absolute maximum of 50mA is set per GPIO, for example: GPIO0 can go max of 50mA and GPIO1 can also max 50mA at the same time so the total is 100mA. Please note TI recommends a max of 25mA per GPIO pin to meet datasheet specs and anything over this may not behave as intended but will still function.
Important parameter to also consider here: Icc through GND is max of 200mA so you should be careful not to pull too much current through the GPIOs AND SDA/INT pins. So if you have all GPIOs pull 25mA and SDA pulls low, you will exceed maximum current through GND.
Another thing you may want to take into consideration is how the junction temperature will be affected. When you start to sink larger amounts of current into or out of this device, you will increase the junction temperature. If the ambient temperature is also high (your end equipment is in a hot area) this will push the junction temperature higher and you may exceed the allowable maximum junction temperature and damage the device.
Thanks,
-Bobby
