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I do not recommend to tie both inputs to GND. This will make the device output state unstable promoting oscillation.
I also do not recommend GND with the other input floating. The internal 100 Ohm resistive termination will allow both the +/- inputs to have roughly the same voltage level. With little or no voltage difference on the input, the device output will be unstable.
If the inputs are unused, I recommend to tie one input side to GND. Tie the other input to VDD through a 2.2K resistor. This will allow enough voltage difference for a very stable output state.
