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TUSB1046A-DCI: pull-up sequence

Part Number: TUSB1046A-DCI

Hi, Team,

A customer will use TUSB1046A-DCI with TPS65987DDH. This is question for TUSB1046A-DCI pull-up. The below pin are pulled-up by I2C Master(TPS65987DDH). Is it ok to turn off TUSB1046A-DCI when I2C Master is power on?

FLIP/SCL
CTL0/SDA
CTL1/HPDIN

Best Regards,
Satoshi Yone