The DS280MB810 datasheet illustrates the expected device Vout/Vin linearity in Figs 1 and 2. Those figures indicate that the graphs apply (only) for straight-thru mode.
How would the graphs be expected to be different when operating in any of the non-straight-thru modes (crossover and mux/fanout)?
What other datasheet characteristics might be expected to be affected when not using straight-thru mode?