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SN65176B: SN65176B damage issue

Part Number: SN65176B

Dear all:

   50PCS sample board, all of SN65176B damage,replce use others production batch, test ok! the below test impedance to gnd's contrast,if have good advices for the issue.thank you!

pin       normal    abnormal1   abnormal2   abnormal3

pin1    0,659        infinity           infinity        infinity

others pin's impedance is normal.

Abnormal IC, main board insert power, but don't press power up key,PIN4 votage is 1.8V, PIN8 votage is 0.8V, when press power up key, SN65176B smoke and damage.

Normal IC, main board insert power, but don't press power up key,PIN4 votage is 3.3V, PIN8 votage about is 0V, when press power up key, SN65176B normal operate.

MCU support 3.3V  stand-by power to PIN4 and PIN8 5V don't power up when don't press power up KEY.the below is the sch.