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TS3USB221A: TS3USB221A Mux Switch and VBUS

Part Number: TS3USB221A

I can't seem to find any info on the following. When adding a mux to connect two peripherals to a host using the TS3USB221A mux, does one need to worry about VBUS being switched as well? So, when I enable peripheral one via the mux, does that mean i need to switch off VBUS to peripheral 2, such that only peripheral 1 gets VBUS. I worry about enumeration and device detection as I turn off one peripheral and I enable the other via the mux. 

Thank you.