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DS90UB953-Q1: I2C high-time and low time

Part Number: DS90UB953-Q1

How long does it take to reflect the  I2C high time/Low time setting change at 953 after sending the command from remote I2C via 954? 

I want to re-write the I2C high-time/Low time setting periodically to ensure that the I2C speed is target value. Is there any restriction to re-write at the same register like this?