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TUSB3410: [RS232] Legacy hardware flow control

Part Number: TUSB3410

Dears,

       Have you ever heard the "legacy Hardware Flow Control"?

       The control mechanism is described as below. 

        Does TUSB3410 can support this communication flow? Or we need to use traditional uart to rs232 interface IC controlled by the comupter?

It's kind of you to help on this.

Thanks

 BR

Edward