Hi TRX expert,
My cusotmers are using PCA9306 for +3.3v_STBY to 1.8v I2C bus lever translator, and +3.3v_STBY I2C device is master, 1.8v I2C device is slave.
+3.3v_STBY is standby power, 1.8v is main power, which means +3.3v_STBY is always on, 1.8v is only on when blade host power on.
So please help check if MEZZ_I2CA_SCL/SDA I2C master bus is tied to GND or other undetermined state when 1.8v is off. Because there are other I2C devices connected to MEZZ_I2CA_SCL/SDA I2C master bus with standby power.