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TUSB4020BI: controlling on/off of downstream communication by I2C

Part Number: TUSB4020BI


Hello experts,

I got question about TUSB4020BI use case from customer.
They plan to use TUSB4020BI on 1 board. (No need USB connector)
Depends on situation, they need to control on/off of downstream communication.
Is it possible to do by I2C only? or SMBus is required?
Thanks and best regards,
Ryo Akashi