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I think I may be missing something. Normally clock stretching would occur if a slave device isn't able to process data from a master device fast enough, so it delays SCK transitions accordingly. This generally isn't an issue for an IO expander like TCA9554A - as long as you keep SCL below the upper limit recommended by the datasheet, the I2C read/write operations will work. Why would you want clock stretching in this case? If the concern is how the device might respond if other slaves perform clock stretching, then I can at least confirm that this will have no adverse effect on TCA9554A.
