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TRS3223-Q1: Over voltage on input reaction

Part Number: TRS3223-Q1

On the datasheet for the TRS3223QPWRQ1 it states that the maximum input voltage is 20V, however what would happen if let's say 45V got applied instead. Our main concern is what would happen to the power supply pin (Would it get shorted/fused together to protect the line?), however it would be good to know what happens to all the pins in terms of safety.