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DS90UB948-Q1: Can Host CPU communicate and control remote I2C slaves connected with DS90UB948 Deserializer?

Part Number: DS90UB948-Q1

Hello Team,

The below picture is our requirement.

Can we control all the remote i2c devices (Sensot,MCU and Display) connected with 948, from HOST CPU?

Is it similar like this?

How to get i2c address of multiple slave devices and control with HOST CPU?Is it possible?