Part Number: ISOUSB211
Hi Team,
I am planning to use the ISOUSB211DPR USB 2.0 isolator in the board design.
The signal flow is as follows: the board receives the USB signal from the host PC through an upstream USB Type-A connector. The signal is then isolated using the ISOUSB211DPR and routed to a 1:4 USB 2.0 hub. Three downstream hub ports are connected to three USB Type-A connectors with ESD protection. The fourth hub port is used for a one-wire interface and is routed through an additional USB isolator, followed by a USB-to-UART converter and a UART-to-one-wire converter before reaching the header.
On the upstream side, the isolator power is derived from the VBUS supplied through the connector. For the isolated side supply, please confirm whether it is preferable to use a 3.3 V rail generated from an isolated DC-DC converter or from the on-board 3.3 V LDO. Additionally, for the downstream USB connectors, an isolated 5 V supply has been provided to prevent interference with on-board circuitry. Please confirm if this approach is appropriate.
The USB interaface block diagram is shared below.

Regards,
Abhishek

