Thanks for info.
Will this Level translator TXB0108YZPR will support I2C 3.4MHz?
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Since this is a drastic subject change, I moved the post to a new thread.
The TXB family of logic will not support I2C because I2C is an open-drain based communication protocol. I believe the TXS family of auto-bidirectional logic translators will support it. Do you know the expected parasitic capacitance (ie capacitive load) that will be applied to the translator?