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SN74AVC4T245: CAN I USE SINGLE SN74AVC4T245 FOR BOTH DIRECTION?

Part Number: SN74AVC4T245

Tool/software:

Hi

I am using SN74AVC4T245 Translation transceiver. can I use 1A1 and 1A2, B to A direction and 2A1, 2A2   A to B direction simultaneously. is it possible without effecting the dataflow?

Regards

P Prasanth