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LSF0204 pull-up resistor

Hi,

could you please clarify where I (must) need to put pull-up resistor??

 only case 4 is bi-directional.

  1. MCU UART Tx(Push pull) --> LSF0204RUTR A side --> LSF0204RUTR B side --> Peripheral UART Rx
  2. MCU UART Rx <-- LSF0204RUTR A side <-- LSF0204RUTR B side <-- Peripheral UART Tx 
  3. MCU GPIO Tx(Push pull) --> LSF0204RUTR A side --> LSF0204RUTR B side --> Peripheral GPIO Rx
  4. MCU I2C Data <--> LSF0204RUTR A side <--> LSF0204RUTR B side <--> Peripheral I2C Data
  5. MCU I2C Clock --> LSF0204RUTR A side --> LSF0204RUTR B side --> Peripheral I2C Clock

 please let me know each side, A,B whether pullup resistor is needed or not.

and if there's no need to use pullup resistor, then should I just tie the pin with Vcc directly? or GND? or Open?

Thanks!