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TXS0102: 14 bit level shifter

Part Number: TXS0102

Hi team,

Since customer need to have fourteen signal to have level transfer , so we would like to know if it is appropriate to select 4 bit part 3 pcs and 2 bit 1 pcs for design?

Is there any timing difference?

Or we have to select  4 bit part 4 pcs for synchronization?