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SN74AXC8T245: How to deal with the unused Pin

Part Number: SN74AXC8T245

Hi Team,

We designed a circuit shown in the picture:

1. The maximum data rate from B1 and B2 is 125MHz, can it have such high data rate?

2. What should we do with the unused pins? Should they be left float or grounded? If grounded, should they connect with ground directly or through a resistor?

Thanks

Hao