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SN74LVC8T245DBR - 8-bit dual-supply bus transceiver

Hi,

I am using one of the SN74LVC8T245DBR chips, and I want to be able to control the direction using a digital output line (at 3.3v).

I see in the data sheet that the direction pin is designed to be either GND or VCCA, but I want VCCA to be 5v, and direction to be 3.3v.

I see that VCCA (and therefore direction) can be as low as 1.65v, but is it okay to have them be at different levels?

Thanks,

Mike