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TXS0108E: High level present in a pin of the non-powered IC can damage it?

Part Number: TXS0108E

I'm using a TXS0108E to convert from 5V to 3.3V and vice versa

In the datasheet, in section 6, I read the following:

Voltage applied to any output in the high-impedance or power-off state, VO:

A port :

     MIN: –0.5V
     MAX: 4.6V 

B port:

     MIN: –0.5V
     MAX: 6.5V

Voltage applied to any output in the high or low state, VO

A port:

    MIN: –0.5 
    MAX: VCCA + 0.5 V

B port:

    MIN: –0.5 
    MAX: VCCB + 0.5 V

Some of pins in B port are energized (Voltage at the pin near 4V) when the IC is not powered at all ( VCCB near 0.4V ). So I was wondering, would this be a problem ?  Can it damage the IC or some pin ?