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TXS0104E: TXS0108E Connect TXS0104E Problem

Part Number: TXS0104E
Other Parts Discussed in Thread: TXS0108E

Hi :

I would like to use TI TXS0104E and TXS0108E, please help to answer a few questions, thank you.

1.Is it ok to use two level conversion chips in series?

The operational scenario is as follows

A Board: TXS0108E&TXS0104E

B Board:TXS0104E

A Board TXS0108E A4&A5 Pin connect  B board  B1&B2 Pin
A Board TXS0104E A3&A4 Pin connect  B board  B3&B4 Pin

2.Is this series of chips suitable for serial communication? Is there any more suitable recommendation?

BR

Sunny