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TXB0104-Q1: Connection

Part Number: TXB0104-Q1

My customer asks: 

The TXB0104-Q1 is used for SPI voltage translation. In the datasheet,SCES727A the typical application schematic diagram shows  the System (Master) Controller is connected at Port-A and the driven device (Slave) is connected at Port-B.

What if the Master Controller (5V) is connected at Port-B and the Slave - at Port-A (3.3V)?

Is this possible? 

BR Josef