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TM4C1294NCPDT: Disabling a GPIO interrupt from ISR

Part Number: TM4C1294NCPDT

Tool/software:

Dear SupportTeam,

Input signal is a pulse, we need an interrupt to be triggered on first rising edge only. Can I disable an interrupt(GPIO_disableInt) from ISR on receiving first interrupt?

There will be multiple instances when such pulsed input signals need to be processed and there are definite operations that would trigger these pulses, so I know when to re-enable an interrupt. 

Is there any better way to handle this scenario?

Thank you for your answer.

Regards

Abhijit