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Is it possible to run a program in RM48_USB_STICK without usb connexion?

I developed an evaluation robot controlled by a RM48_USB_STICK.
When the RM48_USB_STICK is connected to a PC, the program is well starting.
If I connect only the USB power to the 5V power supply of the robot mother board the program does not start.
Is it possible to make the robot working in stand alone? 
Thanks a lot for your help
Kind regards.