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TMS320F280049C: MCU fail. Vdd shorted to Vss

Part Number: TMS320F280049C

Hi all,

I'm working on a "powertrain" project (+48V battery supply). Six months ago, I had developed my custom board with F280049 MCU.

In this months of tests I had 2 times same failure. Yesterday last occourence. 3V3 power supply goes to GND and MCU become hotter without particular reason. No other components are broken.

After removing MCU I can see that VDDs pins are shorted to VSSs. If I replace MCU and reflash it, all the system restart to work without other issue.

I attach my schematic. Have I made connection errors? What can be the causes of a similar failure?

Best regards,