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DSP Running at Exactly 50.000MHz

Other Parts Discussed in Thread: TMS320C5535

I want to supply the TMS320C5535 CLKIN with an external 5.000MHz (or 10.000MHz) and have it operate at exactly 50.000MHz.  Would there be a problem with this?  Wouldn't the I2C boot-loading routine still function (but just operate at slower speed)?

Thanks,

Sheldon