OPA2378: What is a replacement

The closest replacement of OPA2378 would be an auto-zero OPA2335, chopper OPA2387 or linear op amp OPA2391. 

I need a drop in replacement since the OPA2378 is not available..

Unfortunately, the only other dual op amp in SOT-23-8 is a micro-power OPA2369 with much lower bandwidth and much higher offset and drift - see below.

That is my dilemma. Will the OPA2378 SOT 23-8 be available soon? There are 19 of these on my current PCBA and at this time it is unfeasible to rev the design.  

You might look at the OPA2348, I think that is a close dual in a SOT23-8. RRIO but the Vos is much higher. 

However, if you use 4.5V or higher supply voltage, we have a direct replacement available right now - OPA2186.  Btw, DCN and DDFare both SOT-23-8 packages with the distinction being that DDF has a lower (THINer) profile than DCN.

My power supply is 3.3v

Unfortunately, you cannot use OPA2186 with Vs of 3.3V