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AMC1311: Using an isolation amplifier with Vdd1 > Vdd2.

Part Number: AMC1311

Is it possible to configure an isolation amplifier, e.g. ADuM3195, such that Vdd1, on the output side, is higher than Vdd2 on the input side?

It does not seem to work in Spice, but that might not mean that it cannot work in the physical universe.

Thanks,

Lewis