Part Number: THS3491
Other Parts Discussed in Thread: OPA387, OPA891, , OPA814, OPA810
Tool/software:
Introduction
Hello TI Engineers and Community,
I am a lab technician working in a chemical biology lab, where I dabble in using embedded systems for hardware control. While I am familiar with basic circuit design, I mostly use digital circuitry and I am new to analog circuitry. Thus, I'm seeking expert guidance to ensure my design is sound. I greatly appreciate the time and effort of those who assist me in troubleshooting and improving this circuit.
Project Overview
Our lab is working on a specialized biotransistor that relies on precisely bridging a single single-walled carbon nanotube (SWCNT) between two electrodes. This is achieved using dielectrophoresis (DEP) with an 8 MHz, 8 Vpp AC field, which aligns the nanotube across the electrodes. To prevent multiple nanotubes from bridging, I am implementing lock-in amplification to detect when a nanotube successfully completes the circuit.
The detection method (a PDF of this publication is visible in the linked Google Drive folder) follows a published approach where a small 1 kHz, 100 mVpp AC reference signal is superimposed on the 8 MHz signal. The combined signal also has a small DC bias. However, the research paper does not disclose the circuit topology, so I have designed my own analog front end to generate the required signal.
Circuit Overview
I have designed an analog signal path that accomplishes the following:
-
Power Supply:
- The VG2 power supply by GoldPoint Level Controls provides a split-rail virtual ground system (schematic label:
EXTERNAL_PWR_VGND). - An ADP7182 LDO provides -2.5V relative to
VGND. - An ADP7102 LDO provides +2.5V relative to
VGND. The +-2.5 V is for the OPA387 bias voltage buffer.
- The VG2 power supply by GoldPoint Level Controls provides a split-rail virtual ground system (schematic label:
-
Bias Voltage Generation:
- An adjustable voltage divider and an OPA387 voltage follower generate a bias voltage from -2V to VGND.
- This bias voltage is inverted in the summing amplifier, making it a positive bias in the final output.
-
Summing Inverting Amplifier (OPA891):
- The OPA891 voltage-feedback amplifier sums three input signals:
- Bias voltage (
Vbiasfrom OPA387) - 8 MHz, 8 Vpp signal from
AWG_1 - 1 kHz, 100 mVpp signal from
AWG_2
- Bias voltage (
- All input signals are divided by half due to 49.9Ω termination resistors.
- Request: Please verify that the OPA891 is correctly configured to sum all inputs with a gain of -1 per input.
- Example Calculation: If
Vbias = -1V,VAWG_1 = -2V, andVAWG_2 = -1V, the expected output should be 4V.
- Example Calculation: If
- The OPA891 voltage-feedback amplifier sums three input signals:
-
Active Buffer Stage (THS3491):
- A THS3491 high-speed op-amp acts as an active buffer to drive a high-capacitance load (~400 pF).
- The load resistance will likely range from hundreds of kΩ to ~1 MΩ.
- The OPA891 and THS3491 share 6.8 µF of decoupling capacitance for space efficiency.
- Request: Please verify that the THS3491 is correctly configured as a non-inverting buffer with a gain of 2.
- Additionally, I’d appreciate feedback on my chosen gain, feedback, and isolation resistor values (or if better alternatives exist).
-
LDO Power Verification (ADP7102 & ADP7182):
- Request: While I believe my ADP7102 (+2.5V) and ADP7182 (-2.5V) LDO configurations are correct, I'd appreciate confirmation that they will provide stable output voltage as implemented.
- If TI engineers recommend checking with Analog Devices, I’d be happy to do so.
Attachments & Design Considerations (These are all in the linked Google Drive folder.)
- Schematic: Provided as a high-resolution PNG export from Fusion 360.
- Datasheets: Relevant component datasheets are attached.
- Component Sizes:
- All resistors and capacitors are 0805 except for the tantalum capacitors.
- Unless this critically affects op-amp performance due to parasitic inductance, I’d prefer to keep this footprint for ease of soldering.
- Minor harmonic distortion is acceptable if considering high frequencies. After all, my frequencies of interest are below 10 MHz.
Final Thoughts
I deeply appreciate the time and expertise of the TI engineers and community members reviewing my design. This project is my first complex analog circuit, and I want to ensure I'm on the right track.
Please let me know if there are any additional details I can provide. Thank you in advance for your insights! If I haven't made critical mistakes, I'll begin laying out the board.E2E_Support_Docs_THS3491.zip
Best regards,
-Arjun



