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Cuurent Source Topology

Other Parts Discussed in Thread: TIPD107

My name is Sang Yun Bang, and I am a graduate research assistant at New York University. 
I am not sure how much information need to provide for the question Meanwhile I briefly explain the issue for now. 
We are developing bio-electronics for the research. Especially, in our all-in-one measurement PCB board project, we are facing difficulties on bi-directional current source topology. The component of LTC6082, from Linear Technology, has been used for the previous version. However, since we are targeting 0 to 300nA with the resolution of 1 nA, the topology was unstable to implement on our PCB board. 
I would like to have the recommendation from the industries' expert for the TI chip and design. 
I will really appreciate any help and suggestion.