Can I use in vacuum?

For devices that are not space rated, outgassing is not tested, and will probably happen.

Use space-rated devices (see the Space Guide), or at least devices in hermetically-sealed ceramic packages (CDIP, CFP, LCCC).

Hi Ladisch-san

Thank you for your prompt reply.

I understand.

I have a additional question.

Is there a possibility that gas will damage the device or destroy it?

Would you please  provide the information if you have?

Best regards,

Higa

Hi Ladisch-san

Do you have any update?

I would appreciate it if you could reply as soon as possible. 

Best regards,

Higa

I have no information about that. But when TI makes the effort to prevent outgassing in space-rated devices, then there is probably a reason for that.

However, en.wikipedia.org/wiki/Outgassing#In_a_vacuum implies that the main problem is that other devices are affected, and Semiconductor Packing Methodology says that vacuum can be used to remove moisture from MSL ≥2 packages.

I guess you need an answer from a TI employee.