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Thanks!
Hi Junlong,
I'll comment about your questions below:
1. Yes, analog inputs can be routed in different ways and differential is one of them. You can see the routing scheme in the GUI diagram:
2. The Class-D output SPKP and SPKM is always differential, the speaker is connected in a BTL connection.
Best regards,
-Ivan Salazar
Applications Engineer - Low Power Audio & Actuators