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TPA3116D2-Q1: Doubt about designing procedure

Part Number: TPA3116D2-Q1

Hello, thanks for taking the time for helping me with this doubt.

I want to design an audio power amplifier using the TPA3116D2-Q1. I had read the datasheet but is not clear to me the design procedure explained there. How should I do the calculation for identifying which of the gain should I use?

I want to design for two different kinds of load situations, both of them with mono output. For one of them, I have an RL = 4 ohm and the desired output power of 80 Wrms, the second option is an RL = 8 ohm and desired power of 40 Wrms.

How do I set the proper gain for the system to cover the desired output powers (there will be two conditions of output power that I should change with something like dip switches)? I´m not also clear how should I specify my required power supply voltage.

Thanks