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LMX2595: Connect it to STM32L452CEU3

Part Number: LMX2595


Tool/software:

If I want to control this synthesizer using STM32L452CEU3 vis SPI protocol can you help me with this and tell me what are the steps I need to do it because I am a bit confused about alot of details that if I need to set all the required registers to get the needed frequency through sending their values through spi, do I have to do this each time or not? 
also I need to know if I have to map these regisers in the code or not.